| 摘要: |
| 就现代质谱法在药物代谢物的结构鉴定与定量分析、体内药动学高通量筛选和药物生物利用度的测定等药物代谢动力学方面进行了综述，指出现代质谱法在药动学研究中有广阔
的应用前景。 |
| 关键词: 质谱法 药物代谢动力学 生物样品分析 |
| DOI：10.11724/jdmu.2005.01.27 |
| 分类号:R969.1 |
| 基金项目: |
|
| Application of contemporary mass spectrometry in pharmacokinetic studies |
|
QU Bin1, JIANG Bao-na2
|
|
1.College of Pharmacy, Dalian Medical University, Dalian 116027, China;2.Department of Graduate, Dalian Medical University, Dalian 116027,China
|
| Abstract: |
| Applications of contemporary mass spectrometry in pharmacokinetics have been reviewed, including metabolite structure identification and quantitation analysis, high throughput screening techniques in pharmacokinetics and drug bioavailability studies. Mass |
| Key words: mass spectrometry pharmacokinetics bio-analysis |
