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| 脑膜瘤临床病理分析 |
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张迎霞1, 唐建武2, 王燕霞3
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1.大连大学,医学院,辽宁,大连,116622;2.大连医科大学中日临床病理中心辽宁,大连,116027;3.大连市中心医院,辽宁,大连,116030
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| 摘要: |
| [目的]探讨脑膜瘤临床病理特征和预后特点.[方法]采用光镜、电镜和免疫组化方法.[结果]脑膜瘤55例;复发7例,脑膜内皮型12例,过渡型13例,纤维型14例,砂粒体型7例,血管瘤型3例,微囊型4例,分泌型2例.Vim,EMA,ER,PR,NSE均不同程度表达,GFAP及C-erbB-2均阴性.[结论]发现内皮型脑膜瘤可能增殖、分化能力较强,可能容易复发,预后较不良. |
| 关键词: 脑膜瘤 免疫组织化学 电镜 |
| DOI：10.11724/jdmu.2003.02.09 |
| 分类号:R739.45 |
| 基金项目: |
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| Clinical pathology analysis on meningiomas |
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ZHANG Ying-xia1, TANG Jian-wu2, WANG Yan-xia3
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1..Medicine School of Dalian University,Dalian 116622, China;2.Sino-Japen Clinicopathologic Centre,Dalian Medical University,Dalian 116027 ,China;3.Centre Hospital of Dalian,Dalian 116030， China)
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| Abstract: |
| To study the clinical Pathology stigmata and the Prognoses behavior of the meningioma. ［Methods］ Use light-microscope、electron microscope and immunohistochemical method. ［Results］ In 55 cases of meningioma ,including 7 recurrent cases,12 cases of epithelial type, 13 of transitional type, 14 of fibrillar type,7 of grit type,3 of angioma type,4 of microcyst type, 2 of secretory type. Vim，EMA，ER，PR，NSE were expressed in vary degree. GFAP、C-erbB-2 were negative. ［Conclusion］ The authors found that the epithelial type may have strong er ability of proliferation and differentiation, they maybe relapse easily, and may have bad prognosis comparatively. |
| Key words: meningioma immunohistochemistry electron microscope |