| 摘要: |
| 目的:观察银杏叶黄酮的降血脂作用.方法:用高血脂饲料喂养SD大鼠,制备高血脂症大鼠模型,银杏叶黄酮两个剂量组每日灌胃给药.以丹香降脂颗粒为阳性对照组,高血脂模型组给予等容量NS .于给药第14天和第28天分别取血测定血清总胆固醇(TC)和甘油三脂(TG)指标 .结果:银杏叶黄酮组TC、TG水平明显降低(P＜0.01).结论:银杏叶黄酮有较明显的降血脂作用. |
| 关键词: 银杏叶黄酮 血脂 高血脂大鼠模型 |
| DOI：10.11724/jdmu.2001.03.08 |
| 分类号:R972+.6 |
| 基金项目: |
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| Effects of Ginkgoliloba leave flavonoids on blood lipid le vel in high lipid rats |
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LI Chuan-xun, ZHOU Qin, GAO Guang-you
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Department of Pharmacology,Dalian Medical University,Dalian 116027, China)
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| Abstract: |
| To observe the effects of Ginkgoliloba leave flavonoids(GBLF)on decreasing of blood lipid level. Methods:To make use of high blood lipid rats model. The high blood lipid rats randomized classify as four groups:high blood lipid model group (NS),dan xiang jiang Zhi ke li group(1000 mg·kg·-1ig -1),GBLF low dose group (20 mg·kg·-1ig-1), GBLF high dose group (40 mg·kg·-1ig-1). After administration d14 and d18,the blood chlesterol (TC) and Triglyceide (TG) were assayed. Results : GBLF could reduce TC and TG ,apparent difference was found be tween the GBLF group and the model group (Ｐ＜0.01). Conclusion:GBLF may reduce apparently the blood lipid level in rats. |
| Key words: Ginkgoliloba leave flavonoids blood lipid high lipid rat model |